You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has been in medicine for a variety of reasonsDietary fats are large molecules that need to be broken down before they can be absorbed into the body. They are broken down by enzymes called lipases. That is, lipases play an important role in the digestion of dietary fat. When taken with a meal, Xenical interferes with the activity of these enzymes. This allows about 30% of the fat eaten in the meal to pass through the gut undigested. Therefore, your body cannot store these excess calories as fatty tissue or use them as a source of energy. This helps you to reduce your weight by burning up fat that you are already carrying, maintain your lower weight and minimise any weight regain. Losing even small amounts of weight and keeping it off produces additional health benefits for you, especially when you are at risk for other diseases such as heart disease and diabetes. Xenical can also help to improve risk factors, such as high blood pressure, high cholesterol and high blood sugar. If these are not treated, they could lead to other diseases such as hypertension and diabetes. Xenical should be taken in conjunction with a well-balanced calorie-controlled diet and other appropriate measures such as exercise.Active Ingredients:Xenical does not contain sucrose, gluten, tartrazine or any other azo dyes. Active ingredient - orlistat each Xenical capsule contains 120 mg orlistatInactive ingredients
DirectionsTake 1 capsule with each of the 3 main meals per day. It can be taken during the meal or up to 1 hour after the meal is consumed.Warnings & Disclaimers
*** Please note that this product is a Scheduled Medicine in Western Australia. In order to ensure this product is appropriate and safe for you to use, we would appreciate it if you could respond to the following questions for us.
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AUST-R AB HEA 1983-1985A trial was conducted on the efficacy of the capsule in the treatment of obesity. The study showed that 120 mg of 120 capsule capsule once a day (i.e. 120 capsules) had an effect on weight gain. 120 capsules of 120 capsule capsule were found to be as effective as diet and exercise in the treatment of obesity. 120 capsules of 120 capsule capsule were compared with placebo in obese and non-obese patients who had a body mass index (BMI) of less than 18.5. 120 capsules of 120 capsule capsule were found to be as effective as placebo in the treatment of obesity. 120 capsules of 120 capsule capsule were compared with diet and exercise in obese and non-obese patients who had a BMI of 18.5.
Carrying too much weight puts stress on your body which can lead to a variety of health issues.
By reducing the amount of fat cells in your body, you reduce the likelihood of getting very serious conditions such as heart disease, certain cancers, stroke, liver disease, type II diabetes, osteoarthritis and high blood pressure. Being overweight also affects the respiratory system, with side effects such as sleep apnoea and asthma.
If you are overweight or clinically obese then you may suffer from low self-esteem or lack self-confidence and therefore losing weight can help you to regain confidence, increase your self-esteem and lower the risk of depression. It also helps improve the ratio of good to bad cholesterol; reduce blood pressure and inhibit the progression to type II diabetes.
Weight loss can be a difficult and daunting prospect, however clinical studies have shown that those who use Xenical / Orlistat alongside dieting can achieve 50% more weight loss than dieting alone.
Some Handy Tips for a Successful Weight Loss Journey
Above all,don't give up.If you blow it one day, put it behind you as tomorrow is another day! Your weight loss may stop and start but keep going and the outcome will be well worth it.
Intermoxic / & &Thinly thieved top layer, have a clear target level, have a clear aim, but plan meals in advance and shop to your ‘want- unintentionally' goal.
If you give up too soon does not give you the desired outcome. Orlistat is a lipase inhibitor and can cause permanent weight loss of up to 50% from a start
Below are a few tips that you can give your weight loss a try:Orlistat is an effective prescription weight loss pill. Orlistat works by preventing the absorption of dietary fats in the body, which can help to reduce weight and help to lose fat more quickly.
Orlistat, marketed under the brand name Xenical, is the same active ingredient in the Orlistat brand. It is available in 120mg and 60mg capsules, and is available in the following doses:
Orlistat works by blocking about 30 to 50% of the fat your body absorbs from a meal, so the absorption of calories from fat is not affected. Orlistat can help you lose weight by helping you digest fat more efficiently and prevent it from being absorbed by the body. It will not lower your blood pressure. This is because the fat in your diet is excreted from your body through your bowel movements.
You should always take Orlistat at the same time every day, even if you start a new meal. Taking it at the same time each day will have the best effect. Taking it on an empty stomach, like that, will not affect your results. You will need to take it at a low dose and for the shortest time needed to help you lose weight.
If you have any questions or concerns about the drug, talk to your doctor or pharmacist for advice. They will be able to provide advice about whether or not Orlistat is right for you and if it may be the right treatment for you.
Orlistat is a prescription drug and must only be used under the supervision of a healthcare professional.
Orlistat works by preventing the absorption of about 30 to 50% of the fat your body absorbs from food. This fat is fat-soluble and is a natural source of energy. It works best when taken with a large meal. The fat that you eat is fat-free.
Orlistat is available only with a doctor’s prescription and the medication will not cure your weight loss. It is a prescription drug and must only be used under the supervision of a healthcare professional.
You should always take Orlistat at the same time each day, even if you start a new meal.
Show LessOrlistat is a prescription weight loss pill, so it is important to take Orlistat with a full glass of water. This means you should drink plenty of water when you take Orlistat and for a few hours after you consume it.
You should avoid taking Orlistat if you are overweight, have a body mass index (BMI) of 30 or greater, have a history of heart disease, or have a history of liver or kidney disease. Orlistat can make it harder to lose weight. You should not take Orlistat if you have a BMI of 30 or greater.
Orlistat is a prescription drug, so it should only be taken under the supervision of a healthcare professional. Orlistat is not addictive.
Do not use Orlistat if you are pregnant, planning to become pregnant, or breastfeeding. It is not known whether Orlistat passes into breast milk. The drug can pass into breast milk, so it is not recommended that you stop taking Orlistat if you become pregnant.
If you use Orlistat during the last 3 months of pregnancy, it may cause problems. You should consult your doctor about whether you should use Orlistat during your first or second trimester.
Tell your doctor if you use Orlistat regularly or if you use it for longer than recommended.